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Archive du mois : juin 2021

UBI Asia a confirmé son intention de déposer rapidement auprès de l’administration de l’Alimentation et du Médicament de Taiwan une demande d’autorisation d’utilisation d’urgence pour son vaccin contre le Covid-19. © Pixabay 0

[Taiwan] Covid-19 : résultats de phase 2 prometteurs pour un deuxième vaccin taïwanais

Après Medigen Vaccine Biologics le 10 juin, c’était le 27 juin au tour de l’entreprise de biotechnologie taïwanaise United Biomedical (UBI) Asia de dévoiler les résultats prometteurs d’un essai clinique de phase 2 pour son candidat-vaccin contre le Covid-19. UBI Asia a en outre confirmé son intention de déposer rapidement auprès de l’administration de l’Alimentation et du Médicament de Taiwan (TFDA) une demande d’autorisation d’utilisation d’urgence (EUA).

Fig 1. Histogram of intervals between estimated origin dates and first cases (Origin) and between upper bounds of 95% confidence intervals and first cases (95% CI). © DR 0

Dating first cases of COVID-19

Questions persist as to the origin of the COVID-19 pandemic. Evidence is building that its origin as a zoonotic spillover occurred prior to the officially accepted timing of early December, 2019. Here we provide novel methods to date the origin of COVID-19 cases. We show that six countries had exceptionally early cases, unlikely to represent part of their main case series. The model suggests a likely timing of the first case of COVID-19 in China as November 17 (95% CI October 4). Origination dates are discussed for the first five countries outside China and each continent. Results infer that SARS-CoV-2 emerged in China in early October to mid-November, and by January, had spread globally. This suggests an earlier and more rapid timeline of spread. Our study provides new approaches for estimating dates of the arrival of infectious diseases based on small samples that can be applied to many epidemiological situations.