Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study

Auteurs : Qifang Bi, MHS, Yongsheng Wu, MPhil, Shujiang Mei, MPhil, Chenfei Ye, PhD, Xuan Zou, MPhil, Zhen Zhang, MPhil, et al.

Production : Revue The Lancet

The Lancet began as an independent, international weekly general medical journal founded in 1823 by Thomas Wakley. Since its first issue (October 5, 1823), the journal has strived to make science widely available so that medicine can serve, and transform society, and positively impact the lives of people. Over the past two centuries, The Lancet has sought to address urgent topics in our society, initiate debate, put science into context, and influence decision makers around the world. The Lancet has evolved as a family of journals (across Child & Adolescent Health, Diabetes & Endocrinology, Digital Health, Gastroenterology & Hepatology, Global Health, Haematology, HIV, Infectious Diseases, Neurology, Oncology, Planetary Health, Psychiatry, Public Health, Respiratory Medicine, Biomedicine, Clinical Medicine), but retains at its core the belief that medicine must serve society, that knowledge must transform society, that the best science must lead to better lives).

Diffusion : le site de la revue The Lancet

Date : 27 avril 2020

Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan, China, prompted heightened surveillance in Shenzhen, China. The resulting data provide a rare opportunity to measure key metrics of disease course, transmission, and the impact of control measures.

From Jan 14 to Feb 12, 2020, the Shenzhen Center for Disease Control and Prevention identified 391 SARS-CoV-2 cases and 1286 close contacts. We compared cases identified through symptomatic surveillance and contact tracing, and estimated the time from symptom onset to confirmation, isolation, and admission to hospital. We estimated metrics of disease transmission and analysed factors influencing transmission risk.

Source : Qifang Bi, Yongsheng Wu, Shujiang Mei, Chenfei Ye, Xuan Zou, Zhen Zhang et al. , « Epidemiology and transmission of COVID-19 in 391 cases and 1286 of their close contacts in Shenzhen, China: a retrospective cohort study », The Lancet, 27/04/2020. DOI :   https://doi.org/10.1016/S1473-3099(20)30287-5 , PDF :  https://www.thelancet.com/action/showPdf?pii=S1473-3099%2820%2930287-5  (consulté le 28/04/2020)

Photo « à la une » : Attack rate among close contacts, baseline severity, and proportion of cases without fever at initial assessment by age group. © The lancet


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