The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic

Auteurs : Michael Worobey, Joshua I Levy, Lorena Malpica Serrano, Alexander Crits-Christoph, Jonathan E Pekar, Stephen A Goldstein, Angela L Rasmussen, Moritz U G Kraemer, Chris Newman, Marion P G Koopmans, Marc A Suchard, Joel O Wertheim, Philippe Lemey, David L Robertson, Robert F Garry, Edward C Holmes, Andrew Rambaut, Kristian G Andersen

Publication : Science, publié par American Association for the Advancement of Science

Diffusion : site de la revue Science

Date : 26 juillet 2022

Understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in 2019 is critical to preventing zoonotic outbreaks before they become the next pandemic. The Huanan Seafood Wholesale Market in Wuhan, China, was identified as a likely source of cases in early reports but later this conclusion became controversial. We show the earliest known COVID-19 cases from December 2019, including those without reported direct links, were geographically centered on this market. We report that live SARS-CoV-2 susceptible mammals were sold at the market in late 2019 and, within the market, SARS-CoV-2-positive environmental samples were spatially associated with vendors selling live mammals. While there is insufficient evidence to define upstream events, and exact circumstances remain obscure, our analyses indicate that the emergence of SARS-CoV-2 occurred via the live wildlife trade in China, and show that the Huanan market was the epicenter of the COVID-19 pandemic.

Source : Michael Worobey, Joshua I. Levy, Lorena Malpica Serrano [et al.], “The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic”, Science, 26/07/2022. DOI : 10.1126/science.abp87 (Consulté le 27/07/2022).

Voir également :

Jonathan E Pekar, Andrew Magee, Edyth Parker [et al.], “The molecular epidemiology of multiple zoonotic origins of SARS-CoV-2”, Science, 26/07/2022. DOI : (consulté le 27/07/2022).

Photo “à la une” : Une femme passe devant le marché aux animaux de Huanan à Wuhan, le 12 janvier 2020, après sa fermeture en raison de la découverte du coronavirus. © Noël Celis, AFP

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